Name | 4-Methoxysalicylic acid |
Synonyms | AKOS 210-04 ASISCHEM D13357 RARECHEM AL BE 0038 P-MethoxysalicylicAcid 4-Methoxysalicylic acid 2-HYDROXY-P-ANISIC ACID 4-METHOXYSALICYLIC ACID 2-hydroxy-4-methoxybenzoate 2-HYDROXY-4-METHOXYBENZOIC ACID 2-Hydroxy-4-methoxybenzoic acid 2-Hydroxy-4-MethoxybenzoicAcid(P-MethoxysalicylicAcid) |
CAS | 2237-36-7 |
EINECS | 218-801-0 |
InChI | InChI=1/C8H8O4/c1-12-5-2-3-6(8(10)11)7(9)4-5/h2-4,9H,1H3,(H,10,11)/p-1 |
Molecular Formula | C8H8O4 |
Molar Mass | 168.15 |
Density | 1.1816 (rough estimate) |
Melting Point | 158-159°C(lit.) |
Boling Point | 217.07°C (rough estimate) |
Flash Point | 137.8°C |
Solubility | DMSO:33 mg/mL (196.25 mM) |
Vapor Presure | 7.5E-05mmHg at 25°C |
Appearance | White to off-white (Solid) |
Color | Off-white to beige |
pKa | 3.22±0.10(Predicted) |
Storage Condition | Inert atmosphere,Room Temperature |
Refractive Index | 1.4611 (estimate) |
MDL | MFCD00002450 |
Physical and Chemical Properties | White crystals or powder. Melting point 158-159 °c. |
Use | Used as a pharmaceutical Intermediate |
Risk Codes | R36/37/38 - Irritating to eyes, respiratory system and skin. R20/21/22 - Harmful by inhalation, in contact with skin and if swallowed. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. |
WGK Germany | 3 |
RTECS | DH2270000 |
HS Code | 29189900 |
Hazard Note | Irritant |
Reference Show more | 1. Tang W, Li W, Yang Y, Lin X, Wang L, Li C, Yang R. Phenolic Compounds Profile and Antioxidant Capacity of Pitahaya Fruit Peel from Two Red-Skinned Species (Hylocereus polyrhizus and Hylocereus undatus). Foods. 2021; 10(6):1183. https://doi.org/10.3390/food 2. [IF=4.35] Wanpei Tang et al."Phenolic Compounds Profile and Antioxidant Capacity of Pitahaya Fruit Peel from Two Red-Skinned Species (Hylocereus polyrhizus and Hylocereus undatus)."Foods. 2021 Jun;10(6):1183 |
Use | 4-methoxysalicylic acid is a non-competitive mushroom tyrosinase activity inhibitor. Used as a pharmaceutical intermediate |
biological activity | 2-Hydroxy-4-methoxybenzoic acid is a derivative of methoxybenzoic acid. acid is a potential biomarker. |